Biotech · Public company · Seattle, WA, US
Aptevo Therapeutics Inc.
Ticker APVO · SEC CIK 0001671584
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Clinical trials51 recruiting or active
Pipeline programs15From trials and the company's site
Disclosed deals0None found yet
Cash runwayNot availableNo recent cash burn filed
Pipeline15
- 15 mg/kg TRU-016 and bendamustinePhase 2 · Chronic Lymphocytic Leukemia (CLL)ClinicalTrials.gov · fetched Nov 12, 2026
- 20 mg/kg TRU-016 and bendamustinePhase 2 · Chronic Lymphocytic Leukemia (CLL)ClinicalTrials.gov · fetched Nov 12, 2026
- ALG.APV-527Phase 2 · Solid TumorClinicalTrials.gov · fetched Nov 12, 2026
- BendamustinePhase 2 · Chronic Lymphocytic Leukemia (CLL)ClinicalTrials.gov · fetched Nov 12, 2026
- TRU-016 and bendamustinePhase 2 · Chronic Lymphocytic Leukemia (CLL)ClinicalTrials.gov · fetched Nov 12, 2026
- 10 mg/kg TRU-016 + RituximabPhase 1 · Chronic Lymphocytic LeukemiaClinicalTrials.gov · fetched Nov 12, 2026
- 20 mg/kg TRU-016 + RituximabPhase 1 · Chronic Lymphocytic LeukemiaClinicalTrials.gov · fetched Nov 12, 2026
- APVO436Phase 1 · Acute Myeloid Leukemia (AML)ClinicalTrials.gov · fetched Nov 12, 2026
- AzacitidinePhase 1 · Acute Myeloid Leukemia (AML)ClinicalTrials.gov · fetched Nov 12, 2026
- ES414Phase 1 · Prostate CancerClinicalTrials.gov · fetched Nov 12, 2026
- TRU-016 10-20 mg/kg + bendamustinePhase 1 · Chronic Lymphocytic LeukemiaClinicalTrials.gov · fetched Nov 12, 2026
- TRU-016 10-20 mg/kg + ibrutinibPhase 1 · Chronic Lymphocytic LeukemiaClinicalTrials.gov · fetched Nov 12, 2026
- TRU-016 20 mg/kg + ObinutuzumabPhase 1 · Chronic Lymphocytic LeukemiaClinicalTrials.gov · fetched Nov 12, 2026
- TRU-016 6-20 mg/kg + idelalisib + rituximabPhase 1 · Chronic Lymphocytic LeukemiaClinicalTrials.gov · fetched Nov 12, 2026
- VenetoclaxPhase 1 · Acute Myeloid Leukemia (AML)ClinicalTrials.gov · fetched Nov 12, 2026
Clinical trials5
- APVO436 Phase 1b/2 Study in Patients With Newly Diagnosed AMLPHASE1 · RECRUITING · started Oct 1, 2024ClinicalTrials.gov NCT06634394 · fetched Nov 12, 2026
- ALG.APV-527 First-in-human StudyPHASE1_PHASE2 · UNKNOWN · started Dec 23, 2022ClinicalTrials.gov NCT05934539 · fetched Nov 12, 2026
- Study of ES414 in Metastatic Castration-Resistant Prostate CancerPHASE1 · COMPLETED · started Jan 1, 2015ClinicalTrials.gov NCT02262910 · fetched Nov 12, 2026
- Phase 1b Safety and Efficacy Study of TRU-016PHASE1 · TERMINATED · started Sep 1, 2012ClinicalTrials.gov NCT01644253 · fetched Nov 12, 2026
- Safety and Efficacy Study of TRU-016 Plus Bendamustine vs. Bendamustine in Relapsed Chronic Lymphocytic LeukemiaPHASE1_PHASE2 · COMPLETED · started Sep 1, 2010ClinicalTrials.gov NCT01188681 · fetched Nov 12, 2026
SEC filings12
- 8-K · 8-KSEC EDGAR · filed Nov 9, 2026 · fetched Nov 12, 2026
- 8-K · 8-KSEC EDGAR · filed Nov 5, 2026 · fetched Nov 12, 2026
- 8-K · 8-KSEC EDGAR · filed Nov 2, 2026 · fetched Nov 12, 2026
- 8-K · 8-KSEC EDGAR · filed Oct 26, 2026 · fetched Nov 12, 2026
- 8-K · 8-KSEC EDGAR · filed Oct 23, 2026 · fetched Nov 12, 2026
- 8-K · 8-KSEC EDGAR · filed Oct 14, 2026 · fetched Nov 12, 2026
- 8-K · 8-KSEC EDGAR · filed Sep 24, 2026 · fetched Nov 12, 2026
- 8-K · 8-KSEC EDGAR · filed Sep 23, 2026 · fetched Nov 12, 2026
- 424B4 · 424B4SEC EDGAR · filed Sep 3, 2026 · fetched Nov 12, 2026
- 8-K · 8-KSEC EDGAR · filed Sep 3, 2026 · fetched Nov 12, 2026
- S-1 · S-1SEC EDGAR · filed Aug 21, 2026 · fetched Nov 12, 2026
- 8-K · 8-KSEC EDGAR · filed Aug 21, 2026 · fetched Nov 12, 2026