Biotech · Private company
Cyclerion Therapeutics
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Clinical trials130 recruiting or active
Pipeline programs9From trials and the company's site
Disclosed deals0None found yet
Cash runwayNot availablePrivate: no SEC financials
Pipeline9
- IW-1701Phase 2 · Sickle Cell DiseaseClinicalTrials.gov · fetched Nov 12, 2026
- IW-1973Phase 2 · Diabetes Mellitus, Type 2ClinicalTrials.gov · fetched Nov 12, 2026
- OlinciguatPhase 2 · AchalasiaClinicalTrials.gov · fetched Nov 12, 2026
- [14C]-olinciguatPhase 1 · Healthy VolunteersClinicalTrials.gov · fetched Nov 12, 2026
- [14C]-praliciguatPhase 1 · Healthy VolunteersClinicalTrials.gov · fetched Nov 12, 2026
- ItraconazolePhase 1 · HealthyClinicalTrials.gov · fetched Nov 12, 2026
- IW-1701Phase 1 · HealthyClinicalTrials.gov · fetched Nov 12, 2026
- IW-1973Phase 1 · HealthyClinicalTrials.gov · fetched Nov 12, 2026
- OlinciguatPhase 1 · HealthyClinicalTrials.gov · fetched Nov 12, 2026
Clinical trials13
- A Trial to Evaluate the Effect of Itraconazole (ITZ), a CYP3A4 Inhibitor, on the Pharmacokinetics of the Soluble Guanylate Cyclase Stimulator, Olinciguat (IW-1701), in Healthy VolunteersPHASE1 · COMPLETED · started May 3, 2019ClinicalTrials.gov NCT03892499 · fetched Nov 12, 2026
- A Trial to Study the Absorption, Metabolism, and Excretion of [14C]-Praliciguat in Healthy Male VolunteersPHASE1 · COMPLETED · started Mar 1, 2019ClinicalTrials.gov NCT03818295 · fetched Nov 12, 2026
- A Trial to Study the Absorption, Metabolism, and Excretion of [14C]-Olinciguat in Healthy Male VolunteersPHASE1 · COMPLETED · started Jan 17, 2019ClinicalTrials.gov NCT03795519 · fetched Nov 12, 2026
- A Trial to Evaluate the Effect of Itraconazole (ITZ), a CYP3A4 Inhibitor, on the Pharmacokinetics of Praliciguat (IW-1973) in Healthy VolunteersPHASE1 · COMPLETED · started Apr 12, 2018ClinicalTrials.gov NCT03499106 · fetched Nov 12, 2026
- A Study of the Effect of IW-1701 (Olinciguat), a Stimulator of Soluble Guanylate Cyclase (sGC), on Patients With Sickle Cell Disease (SCD)PHASE2 · COMPLETED · started Dec 22, 2017ClinicalTrials.gov NCT03285178 · fetched Nov 12, 2026
- A Study of the Effect of IW-1973 on the Exercise Capacity of Patients With Heart Failure With Preserved Ejection Fraction (HFpEF)PHASE2 · COMPLETED · started Nov 7, 2017ClinicalTrials.gov NCT03254485 · fetched Nov 12, 2026
- A Study to Evaluate the Soluble Guanylate Cyclase (sGC) Stimulator IW-1973 in Diabetic Nephropathy / Diabetic Kidney Disease as Measured by AlbuminuriaPHASE2 · COMPLETED · started Aug 1, 2017ClinicalTrials.gov NCT03217591 · fetched Nov 12, 2026
- Study of IW-1701, A Stimulator of Soluble Guanylate Cyclase (sGC), in Patients With Type I or II AchalasiaPHASE2 · TERMINATED · started Apr 6, 2017ClinicalTrials.gov NCT02931565 · fetched Nov 12, 2026
- Trial of IW-1973, A Stimulator of Soluble Guanylate Cyclase (sGC) in Patients With Stable Type 2 Diabetes and HypertensionPHASE2 · COMPLETED · started Feb 28, 2017ClinicalTrials.gov NCT03091920 · fetched Nov 12, 2026
- A Phase 2 Trial of IW-1973, A Stimulator of Soluble Guanylate Cyclase (sGC), in Patients With Stable Type 2 Diabetes and HypertensionPHASE2 · COMPLETED · started Sep 1, 2016ClinicalTrials.gov NCT02906579 · fetched Nov 12, 2026
- A Trial of IW-1701, A Stimulator of Soluble Guanylate Cyclase (sGC), in Healthy SubjectsPHASE1 · COMPLETED · started May 1, 2016ClinicalTrials.gov NCT02792998 · fetched Nov 12, 2026
- Trial of IW-1973 (A Stimulator of Soluble Guanylate Cyclase (sGC)) in Healthy VolunteersPHASE1 · COMPLETED · started Nov 1, 2015ClinicalTrials.gov NCT02616861 · fetched Nov 12, 2026
- Trial of IW-1701 (A Stimulator of Soluble Guanylate Cyclase (sGC)) in Healthy VolunteersPHASE1 · COMPLETED · started Oct 1, 2015ClinicalTrials.gov NCT02572349 · fetched Nov 12, 2026