Biotech · Public company · The Woodlands, TX, US
Lexicon Pharmaceuticals, Inc.
Ticker LXRX · SEC CIK 0001062822
Track this companyFree. Adds Lexicon Pharmaceuticals, Inc. to your Dealase workspace and tells you when its record changes.
Clinical trials254 recruiting or active
Pipeline programs15From trials and the company's site
Disclosed deals0None found yet
Cash runwayNot availableNo recent cash burn filed
Pipeline15
- EmpagliflozinPhase 3 · Type 2 Diabetes MellitusClinicalTrials.gov · fetched Nov 12, 2026
- GlimepiridePhase 3 · Type 2 Diabetes MellitusClinicalTrials.gov · fetched Nov 12, 2026
- Insulin glargine (HOE901)Phase 3 · Type 2 Diabetes MellitusClinicalTrials.gov · fetched Nov 12, 2026
- MetforminPhase 3 · Type 2 Diabetes MellitusClinicalTrials.gov · fetched Nov 12, 2026
- Oral Antidiabetes Drugs (OADs)Phase 3 · Type 2 Diabetes MellitusClinicalTrials.gov · fetched Nov 12, 2026
- SotagliflozinPhase 3 · Heart FailureClinicalTrials.gov · fetched Nov 12, 2026
- SotagliflozinPhase 3 · Type 2 Diabetes MellitusClinicalTrials.gov · fetched Nov 12, 2026
- SotagliflozinPhase 3 · Type 1 Diabetes MellitusClinicalTrials.gov · fetched Nov 12, 2026
- SotagliflozinPhase 3 · Obstructive Cardiomyopathy, HypertrophicClinicalTrials.gov · fetched Nov 12, 2026
- Sotagliflozin (SAR439954)Phase 3 · Type 2 Diabetes MellitusClinicalTrials.gov · fetched Nov 12, 2026
- SulfonylureaPhase 3 · Type 2 Diabetes MellitusClinicalTrials.gov · fetched Nov 12, 2026
- LX9211Phase 2 · Diabetic Peripheral NeuropathyClinicalTrials.gov · fetched Nov 12, 2026
- LX9211Phase 2 · Postherpetic NeuralgiaClinicalTrials.gov · fetched Nov 12, 2026
- LX9211 (blinded)Phase 2 · Diabetic Peripheral Neuropathic PainClinicalTrials.gov · fetched Nov 12, 2026
- SotagliflozinPhase 2 · Cardiac Failure AggravatedClinicalTrials.gov · fetched Nov 12, 2026
Clinical trials25
- CKM For Safe Use of SGLT2i in Type 1 DiabetesPHASE3 · NOT_YET_RECRUITING · started Apr 1, 2027ClinicalTrials.gov NCT07211802 · fetched Nov 12, 2026
- Comparison of Antiplatelet Effects of Sotagliflozin to FDA-approved Antiplatelet DrugsEARLY_PHASE1 · COMPLETED · started Sep 2, 2025ClinicalTrials.gov NCT06933056 · fetched Nov 12, 2026
- Sotagliflozin to Slow Kidney Function Decline in Persons With Type 1 Diabetes and Diabetic Kidney DiseasePHASE3 · RECRUITING · started Oct 31, 2024ClinicalTrials.gov NCT06217302 · fetched Nov 12, 2026
- A Study to Evaluate the Efficacy and Safety of Sotagliflozin in Symptomatic Obstructive and Non-obstructive Hypertrophic CardiomyopathyPHASE3 · ACTIVE_NOT_RECRUITING · started Sep 24, 2024ClinicalTrials.gov NCT06481891 · fetched Nov 12, 2026
- Combination Adjunctive Therapy to Address Multiple Metabolic Imbalances in Type 1 DiabetesPHASE1_PHASE2 · ACTIVE_NOT_RECRUITING · started Sep 9, 2024ClinicalTrials.gov NCT05696366 · fetched Nov 12, 2026
- A Dose-ranging Study in Patients With Diabetic Peripheral Neuropathic Pain (DPNP)PHASE2 · COMPLETED · started Nov 29, 2023ClinicalTrials.gov NCT06203002 · fetched Nov 12, 2026
- Efficacy and Safety of LX9211 in Participants With Postherpetic NeuralgiaPHASE2 · COMPLETED · started Dec 10, 2020ClinicalTrials.gov NCT04662281 · fetched Nov 12, 2026
- Efficacy, Safety, and PK of LX9211 in Participants With Diabetic Peripheral Neuropathic PainPHASE2 · COMPLETED · started Sep 3, 2020ClinicalTrials.gov NCT04455633 · fetched Nov 12, 2026
- Telotristat Ethyl to Promote Weight Stability in Patients With Advanced Stage Pancreatic CancerPHASE2 · COMPLETED · started Apr 17, 2019ClinicalTrials.gov NCT03910387 · fetched Nov 12, 2026
- Effect of Sotagliflozin on Cardiovascular Events in Participants With Type 2 Diabetes Post Worsening Heart Failure (SOLOIST-WHF Trial)PHASE3 · TERMINATED · started Jun 15, 2018ClinicalTrials.gov NCT03521934 · fetched Nov 12, 2026
- Efficacy and Bone Safety of Sotagliflozin 400 and 200 mg Versus Placebo in Participants With Type 2 Diabetes Mellitus Who Have Inadequate Glycemic ControlPHASE3 · TERMINATED · started Feb 19, 2018ClinicalTrials.gov NCT03386344 · fetched Nov 12, 2026
- Effect of Sotagliflozin on Cardiovascular and Renal Events in Participants With Type 2 Diabetes and Moderate Renal Impairment Who Are at Cardiovascular RiskPHASE3 · TERMINATED · started Dec 19, 2017ClinicalTrials.gov NCT03315143 · fetched Nov 12, 2026
- Safety, Tolerability and Pharmacodynamic Activity of Sotagliflozin in Hemodynamically Stable Participants With Worsening Heart FailurePHASE2 · TERMINATED · started Dec 4, 2017ClinicalTrials.gov NCT03292653 · fetched Nov 12, 2026
- Efficacy and Safety of Sotagliflozin Versus Glimepiride and Placebo in Participants With Type 2 Diabetes Mellitus That Are Taking Metformin MonotherapyPHASE3 · COMPLETED · started Dec 1, 2017ClinicalTrials.gov NCT03332771 · fetched Nov 12, 2026
- Efficacy and Safety of Sotagliflozin Versus Placebo and Empagliflozin in Participants With Type 2 Diabetes Mellitus Who Have Inadequate Glycemic Control While Taking a DPP4 Inhibitor Alone or With MetforminPHASE3 · COMPLETED · started Nov 27, 2017ClinicalTrials.gov NCT03351478 · fetched Nov 12, 2026
- Efficacy and Safety of Sotagliflozin Versus Placebo in Participants With Type 2 Diabetes Mellitus Who Have Inadequate Glycemic Control While Taking Insulin Alone or With Other Oral Antidiabetic AgentsPHASE3 · COMPLETED · started Sep 15, 2017ClinicalTrials.gov NCT03285594 · fetched Nov 12, 2026
- Safety and Efficacy Study of Sotagliflozin on Glucose Control in Participants With Type 2 Diabetes, Moderate Impairment of Kidney Function, and Inadequate Blood Sugar ControlPHASE3 · COMPLETED · started Aug 16, 2017ClinicalTrials.gov NCT03242252 · fetched Nov 12, 2026
- A Study to Evaluate Safety and Effects of Sotagliflozin 400 and 200 mg on Glucose Control in Participants With Type 2 Diabetes, Severe Impairment of Kidney Function and Inadequate Blood Sugar ControlPHASE3 · COMPLETED · started Aug 16, 2017ClinicalTrials.gov NCT03242018 · fetched Nov 12, 2026
- Efficacy and Safety of Sotagliflozin Versus Placebo in Participants With Type 2 Diabetes Mellitus on Background of Sulfonylurea Alone or With MetforminPHASE3 · COMPLETED · started Feb 24, 2017ClinicalTrials.gov NCT03066830 · fetched Nov 12, 2026
- Efficacy and Safety of Sotagliflozin Versus Placebo in Patients With Type 2 Diabetes Mellitus Not Currently Treated With Antidiabetic TherapyPHASE3 · COMPLETED · started Nov 11, 2016ClinicalTrials.gov NCT02926937 · fetched Nov 12, 2026
- Efficacy and Safety of Sotagliflozin Versus Placebo in Patients With Type 2 Diabetes Mellitus on Background of MetforminPHASE3 · COMPLETED · started Nov 1, 2016ClinicalTrials.gov NCT02926950 · fetched Nov 12, 2026
- Dose-ranging Study in Patients With Type 1 Diabetes MellitusPHASE2 · COMPLETED · started Jul 1, 2015ClinicalTrials.gov NCT02459899 · fetched Nov 12, 2026
- Efficacy and Safety of Sotagliflozin in Young Adult Patients With Type 1 Diabetes Mellitus and Elevated Hemoglobin A1CPHASE2 · COMPLETED · started Apr 1, 2015ClinicalTrials.gov NCT02383940 · fetched Nov 12, 2026
- Efficacy, Safety, and Tolerability Study of Sotagliflozin as Adjunct Therapy in Adult Patients With Type 1 Diabetes Mellitus Who Have Inadequate Glycemic Control With Insulin TherapyPHASE3 · COMPLETED · started Mar 1, 2015ClinicalTrials.gov NCT02384941 · fetched Nov 12, 2026
- Safety and Efficacy of Sotagliflozin (LX4211) in Patients With Inadequately Controlled Type 1 Diabetes MellitusPHASE2 · COMPLETED · started Feb 1, 2013ClinicalTrials.gov NCT01742208 · fetched Nov 12, 2026
SEC filings12
- 10-Q · 10-QSEC EDGAR · filed Nov 5, 2026 · fetched Nov 12, 2026
- 8-K · 8-KSEC EDGAR · filed Nov 5, 2026 · fetched Nov 12, 2026
- 10-Q · 10-QSEC EDGAR · filed Aug 6, 2026 · fetched Nov 12, 2026
- 8-K · 8-KSEC EDGAR · filed Aug 6, 2026 · fetched Nov 12, 2026
- 10-Q · 10-QSEC EDGAR · filed May 7, 2026 · fetched Nov 12, 2026
- 8-K · 8-KSEC EDGAR · filed May 7, 2026 · fetched Nov 12, 2026
- 8-K · 8-KSEC EDGAR · filed May 6, 2026 · fetched Nov 12, 2026
- 8-K · 8-KSEC EDGAR · filed Apr 30, 2026 · fetched Nov 12, 2026
- 10-K · 10-KSEC EDGAR · filed Mar 5, 2026 · fetched Nov 12, 2026
- 8-K · 8-KSEC EDGAR · filed Mar 5, 2026 · fetched Nov 12, 2026
- 8-K · 8-KSEC EDGAR · filed Feb 2, 2026 · fetched Nov 12, 2026
- 8-K · 8-KSEC EDGAR · filed Jan 29, 2026 · fetched Nov 12, 2026