Biotech · Private company

Mesoblast, Inc.

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Clinical trials251 recruiting or active

Pipeline programs31From trials and the company's site

Disclosed deals0None found yet

Cash runwayNot availablePrivate: no SEC financials

Pipeline31

CorticosteroidPhase 3 · Graft Versus Host DiseaseClinicalTrials.gov · fetched Nov 12, 2026
Infusion of one MPC expanded cord unit and one unexpanded cord unitPhase 3 · Acute Myelogenous LeukemiaClinicalTrials.gov · fetched Nov 12, 2026
Infusion of two unexpanded cord blood units.Phase 3 · Acute Myelogenous LeukemiaClinicalTrials.gov · fetched Nov 12, 2026
PROCHYMAL adult human mesenchymal stem cellsPhase 3 · Crohn's DiseaseClinicalTrials.gov · fetched Nov 12, 2026
Prochymal®Phase 3 · Graft Versus Host DiseaseClinicalTrials.gov · fetched Nov 12, 2026
Prochymal®Phase 3 · Crohn's DiseaseClinicalTrials.gov · fetched Nov 12, 2026
remestemcel-LPhase 3 · Grade B aGVHDClinicalTrials.gov · fetched Nov 12, 2026
Remestemcel-LPhase 3 · Grade B Acute Graft Versus Host DiseaseClinicalTrials.gov · fetched Nov 12, 2026
Rexlemestrocel-LPhase 3 · Degenerative Disc DiseaseClinicalTrials.gov · fetched Nov 12, 2026
Rexlemestrocel-LPhase 3 · Chronic Heart FailureClinicalTrials.gov · fetched Nov 12, 2026
Rexlemestrocel-L + HA mixturePhase 3 · Degenerative Disc DiseaseClinicalTrials.gov · fetched Nov 12, 2026
Sham ComparatorPhase 3 · Chronic Heart FailureClinicalTrials.gov · fetched Nov 12, 2026
Allogeneic Mesenchymal Precursor CellsPhase 2 · Rheumatoid ArthritisClinicalTrials.gov · fetched Nov 12, 2026
CyclosporinePhase 2 · Graft Vs Host DiseaseClinicalTrials.gov · fetched Nov 12, 2026
Lumbar Interbody Fusion with AutograftPhase 2 · Degenerative Disc DiseaseClinicalTrials.gov · fetched Nov 12, 2026
Lumbar Interbody Fusion with NeoFusePhase 2 · Degenerative Disc DiseaseClinicalTrials.gov · fetched Nov 12, 2026
Mesenchymal Precursor Cells (MPCs)Phase 2 · Type 2 DiabetesClinicalTrials.gov · fetched Nov 12, 2026
MethylprednisolonePhase 2 · Graft Vs Host DiseaseClinicalTrials.gov · fetched Nov 12, 2026
NeoFusePhase 2 · Degenerative Disc DiseaseClinicalTrials.gov · fetched Nov 12, 2026
PLF with autograftPhase 2 · Degenerative Disc DiseaseClinicalTrials.gov · fetched Nov 12, 2026
PLF with NeoFusePhase 2 · Degenerative Disc DiseaseClinicalTrials.gov · fetched Nov 12, 2026
posterolateral spinal fusion with instrumentationPhase 2 · Degenerative Disc DiseaseClinicalTrials.gov · fetched Nov 12, 2026
PrednisonePhase 2 · Graft Vs Host DiseaseClinicalTrials.gov · fetched Nov 12, 2026
Prochymal®Phase 2 · Myocardial InfarctionClinicalTrials.gov · fetched Nov 12, 2026
PROCHYMAL®Phase 2 · Type 1 Diabetes MellitusClinicalTrials.gov · fetched Nov 12, 2026
Prochymal® - 2 Million cells/kgPhase 2 · Graft Vs Host DiseaseClinicalTrials.gov · fetched Nov 12, 2026
Prochymal®- 8 Million cells/kgPhase 2 · Graft Vs Host DiseaseClinicalTrials.gov · fetched Nov 12, 2026
Prochymal™Phase 2 · Pulmonary Disease, Chronic ObstructiveClinicalTrials.gov · fetched Nov 12, 2026
Single Dose MPCs InjectionPhase 2 · Degenerative Disc DiseaseClinicalTrials.gov · fetched Nov 12, 2026
Single injection of hyaluronic acidPhase 2 · Degenerative Disc DiseaseClinicalTrials.gov · fetched Nov 12, 2026
TacrolimusPhase 2 · Graft Vs Host DiseaseClinicalTrials.gov · fetched Nov 12, 2026

Clinical trials25

Efficacy and Safety of Rexlemestrocel-L Combined With HA* in Participants With Moderate to Severe Chronic Low Back PainPHASE3 · ACTIVE_NOT_RECRUITING · started Jul 3, 2024ClinicalTrials.gov NCT06325566 · fetched Nov 12, 2026
Study of Mesenchymal Stem Cells for the Treatment of Medically Refractory Ulcerative Colitis (UC)PHASE1_PHASE2 · TERMINATED · started Nov 10, 2020ClinicalTrials.gov NCT04543994 · fetched Nov 12, 2026
Study of Mesenchymal Stem Cells for the Treatment of Medically Refractory Crohn's ColitisPHASE1_PHASE2 · TERMINATED · started Nov 4, 2020ClinicalTrials.gov NCT04548583 · fetched Nov 12, 2026
MSCs in COVID-19 ARDSPHASE3 · TERMINATED · started Apr 30, 2020ClinicalTrials.gov NCT04371393 · fetched Nov 12, 2026
Safety Follow-up of Treatment With Remestemcel-L in Pediatric Participants Who Have Failed to Respond to Steroid Treatment for Acute GVHDPHASE3 · COMPLETED · started Oct 28, 2015ClinicalTrials.gov NCT02652130 · fetched Nov 12, 2026
A Prospective Study of Remestemcel-L, Ex-vivo Cultured Adult Human Mesenchymal Stromal Cells, for the Treatment of Pediatric Participants Who Have Failed to Respond to Steroid Treatment for Acute Graft-Versus-Host Disease (aGVHD)PHASE3 · COMPLETED · started Jun 4, 2015ClinicalTrials.gov NCT02336230 · fetched Nov 12, 2026
Placebo-controlled Study to Evaluate Rexlemestrocel-L Alone or Combined With Hyaluronic Acid in Participants With Chronic Low Back PainPHASE3 · COMPLETED · started Mar 6, 2015ClinicalTrials.gov NCT02412735 · fetched Nov 12, 2026
Efficacy and Safety of Allogeneic Mesenchymal Precursor Cells (Rexlemestrocel-L) for the Treatment of Heart FailurePHASE3 · COMPLETED · started Mar 3, 2014ClinicalTrials.gov NCT02032004 · fetched Nov 12, 2026
P3 Study of Umbilical Cord Blood Cells Expanded With MPCs for Transplantation in Patients With Hematologic MalignanciesPHASE3 · COMPLETED · started Aug 1, 2013ClinicalTrials.gov NCT01854567 · fetched Nov 12, 2026
A Multi-center Study a Single IV Infusion of Allogeneic MPCs in Patients With Rheumatoid Arthritis and Incomplete Response to at Least One TNFα InhibitorPHASE2 · COMPLETED · started Jul 1, 2013ClinicalTrials.gov NCT01851070 · fetched Nov 12, 2026
Safety Study of Mesenchymal Precursor Cells in Type 2 DiabetesPHASE1_PHASE2 · COMPLETED · started Apr 1, 2012ClinicalTrials.gov NCT01576328 · fetched Nov 12, 2026
Safety and Preliminary Efficacy Study of Mesenchymal Precursor Cells (MPCs) in Subjects With Lumbar Back PainPHASE2 · COMPLETED · started Aug 1, 2011ClinicalTrials.gov NCT01290367 · fetched Nov 12, 2026
Evaluation of PROCHYMAL® for Treatment-refractory Moderate-to-severe Crohn's DiseasePHASE3 · COMPLETED · started Nov 29, 2010ClinicalTrials.gov NCT01233960 · fetched Nov 12, 2026
Safety and Preliminary Efficacy Study of NeoFuse in Subjects Requiring Lumbar Interbody FusionPHASE2 · COMPLETED · started Sep 1, 2009ClinicalTrials.gov NCT00996073 · fetched Nov 12, 2026
Prochymal® (Human Adult Stem Cells) Intravenous Infusion Following Acute Myocardial Infarction (AMI)PHASE2 · COMPLETED · started Mar 30, 2009ClinicalTrials.gov NCT00877903 · fetched Nov 12, 2026
Safety and Efficacy Study of NeoFuse in Subjects Requiring Posterolateral Lumbar FusionPHASE1_PHASE2 · WITHDRAWN · started Nov 1, 2008ClinicalTrials.gov NCT00810212 · fetched Nov 12, 2026
PROCHYMAL® (Human Adult Stem Cells) for the Treatment of Recently Diagnosed Type 1 Diabetes Mellitus (T1DM)PHASE2 · COMPLETED · started Jun 11, 2008ClinicalTrials.gov NCT00690066 · fetched Nov 12, 2026
PROCHYMAL™ (Human Adult Stem Cells) for the Treatment of Moderate to Severe Chronic Obstructive Pulmonary Disease (COPD)PHASE2 · COMPLETED · started Mar 20, 2008ClinicalTrials.gov NCT00683722 · fetched Nov 12, 2026
Efficacy and Safety of Prochymal® Infusion in Combination With Corticosteroids for the Treatment of Newly Diagnosed Acute Graft Versus Host Disease (GVHD)PHASE3 · COMPLETED · started Jan 31, 2008ClinicalTrials.gov NCT00562497 · fetched Nov 12, 2026
Study of 3 Doses of NeoFuse Combined With MasterGraft Granules in Subjects Requiring Posterolateral Lumbar Fusion (PLF)PHASE1_PHASE2 · COMPLETED · started Oct 1, 2007ClinicalTrials.gov NCT00549913 · fetched Nov 12, 2026
Evaluation of PROCHYMAL® Adult Human Stem Cells for Treatment-resistant Moderate-to-severe Crohn's DiseasePHASE3 · COMPLETED · started Sep 17, 2007ClinicalTrials.gov NCT00482092 · fetched Nov 12, 2026
Extended Evaluation of PROCHYMAL® Adult Human Stem Cells for Treatment-Resistant Moderate-to-Severe Crohn's DiseasePHASE3 · COMPLETED · started Sep 17, 2007ClinicalTrials.gov NCT00543374 · fetched Nov 12, 2026
Efficacy and Safety of Adult Human Mesenchymal Stem Cells to Treat Steroid Refractory Acute Graft Versus Host Disease (GVHD)PHASE3 · COMPLETED · started Aug 17, 2006ClinicalTrials.gov NCT00366145 · fetched Nov 12, 2026
Safety and Efficacy of Prochymal for the Salvage of Treatment-Refractory Acute GVHD ParticipantsPHASE2 · COMPLETED · started Nov 18, 2005ClinicalTrials.gov NCT00284986 · fetched Nov 12, 2026
Safety and Efficacy Study of Adult Human Mesenchymal Stem Cells to Treat Acute Graft Versus Host Disease (GVHD)PHASE2 · COMPLETED · started Apr 27, 2005ClinicalTrials.gov NCT00136903 · fetched Nov 12, 2026