Biotech · Public company · Bedford, MA, US
Ocular Therapeutix, Inc
Ticker OCUL · SEC CIK 0001393434
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Clinical trials255 recruiting or active
Pipeline programs25From trials and the company's site
Disclosed deals0None found yet
Cash runwayNot availableNo recent cash burn filed
Pipeline25
- AfliberceptPhase 3 · Neovascular Age-related Macular DegenerationClinicalTrials.gov · fetched Nov 12, 2026
- Dextenza Ophthalmic InsertPhase 3 · CataractClinicalTrials.gov · fetched Nov 12, 2026
- Intravitreal injection of axitinib hydrogel implant followed by a second intravitreal injection of the axitinib implant at Week 24Phase 3 · Non-Proliferative Diabetic RetinopathyClinicalTrials.gov · fetched Nov 12, 2026
- Ophthalmic InsertPhase 3 · Open Angle Glaucoma and Ocular HypertensionClinicalTrials.gov · fetched Nov 12, 2026
- OTX-TKIPhase 3 · Neovascular Age-related Macular DegenerationClinicalTrials.gov · fetched Nov 12, 2026
- OTX-TKIPhase 3 · Neovascular Age-Related Macular Degeneration (nAMD)ClinicalTrials.gov · fetched Nov 12, 2026
- OTX-TKI (axitinib implant)Phase 3 · Neovascular Age-Related Macular DegenerationClinicalTrials.gov · fetched Nov 12, 2026
- Prednisolone acetate ophthalmic suspension USP 1%Phase 3 · CataractClinicalTrials.gov · fetched Nov 12, 2026
- Sham/mock procedure of intravitreal injection followed by a second sham/mock procedure at Week 24Phase 3 · Non-Proliferative Diabetic RetinopathyClinicalTrials.gov · fetched Nov 12, 2026
- Single intravitreal injection of axitinib hydrogel implant followed by a mock (sham) injection procedure at Week 24Phase 3 · Non-Proliferative Diabetic RetinopathyClinicalTrials.gov · fetched Nov 12, 2026
- Collagen Punctal PlugPhase 2 · Dry Eye SyndromesClinicalTrials.gov · fetched Nov 12, 2026
- Controlled InsertionPhase 2 · Dry Eye SyndromesClinicalTrials.gov · fetched Nov 12, 2026
- Durysta, Bimatoprost Intracameral Implant 10 µgPhase 2 · Open Angle GlaucomaClinicalTrials.gov · fetched Nov 12, 2026
- OTX-CSIPhase 2 · Dry Eye DiseaseClinicalTrials.gov · fetched Nov 12, 2026
- OTX-DEDPhase 2 · Dry Eye SyndromesClinicalTrials.gov · fetched Nov 12, 2026
- OTX-DEDPhase 2 · Dry EyeClinicalTrials.gov · fetched Nov 12, 2026
- OTX-TIC high dose Travoprost Intracameral ImplantPhase 2 · Open Angle GlaucomaClinicalTrials.gov · fetched Nov 12, 2026
- OTX-TIC low dose Travoprost Intracameral ImplantPhase 2 · Open Angle GlaucomaClinicalTrials.gov · fetched Nov 12, 2026
- Aflibercept/ShamPhase 1 · Neovascular Age-Related Macular DegenerationClinicalTrials.gov · fetched Nov 12, 2026
- Dexamethasone OphthalmicPhase 1 · HealthyClinicalTrials.gov · fetched Nov 12, 2026
- DilatorPhase 1 · HealthyClinicalTrials.gov · fetched Nov 12, 2026
- OTX-TICPhase 1 · Ocular HypertensionClinicalTrials.gov · fetched Nov 12, 2026
- OTX-TKIPhase 1 · Non-proliferative Diabetic RetinopathyClinicalTrials.gov · fetched Nov 12, 2026
- OTX-TKI/ShamPhase 1 · Neovascular Age-Related Macular DegenerationClinicalTrials.gov · fetched Nov 12, 2026
- ShamPhase 1 · Non-proliferative Diabetic RetinopathyClinicalTrials.gov · fetched Nov 12, 2026
Clinical trials25
- Study to Evaluate Long-Term Safety of Intravitreal OTX-TKI (Axitinib Implant) in Participants With Neovascular Age-Related Macular Degeneration Who Successfully Completed 2-Year OTX-TKI-2023-AMD-301 or OTX-TKI-2023-AMD-303 StudyPHASE3 · RECRUITING · started Apr 27, 2026ClinicalTrials.gov NCT07516132 · fetched Nov 12, 2026
- A Study to Evaluate the Efficacy and Safety of OTX-TKI (Axitinib Implant) in Participants With Non-Proliferative Diabetic RetinopathyPHASE3 · RECRUITING · started Nov 17, 2025ClinicalTrials.gov NCT07235085 · fetched Nov 12, 2026
- Study to Evaluate the Efficacy and Safety of Intravitreal OTX-TKI (Axitinib Implant) in Subjects With Neovascular Age- Related Macular DegenerationPHASE3 · ACTIVE_NOT_RECRUITING · started Nov 27, 2024ClinicalTrials.gov NCT06495918 · fetched Nov 12, 2026
- Study to Evaluate the Efficacy and Safety of Intravitreal OTX-TKI (Ocular Therapeutix) (Axitinib Implant) in Subjects With Neovascular Age-Related Macular DegenerationPHASE3 · ACTIVE_NOT_RECRUITING · started Jan 29, 2024ClinicalTrials.gov NCT06223958 · fetched Nov 12, 2026
- OTX-DED for the Short-term Treatment of the Symptoms of Dry Eye Disease (DED)PHASE2 · COMPLETED · started May 11, 2023ClinicalTrials.gov NCT05814757 · fetched Nov 12, 2026
- Study to Evaluate the Safety, Tolerability, and Efficacy of OTX-TKI in Subjects With Moderately Severe to Severe Non-proliferative Diabetic RetinopathyPHASE1 · UNKNOWN · started Jan 15, 2023ClinicalTrials.gov NCT05695417 · fetched Nov 12, 2026
- Efficacy of Dextenza Insert in Upper vs Lower Punctum Following Cataract Surgery With PCIOL.PHASE4 · COMPLETED · started Jun 15, 2022ClinicalTrials.gov NCT05372315 · fetched Nov 12, 2026
- A Study to Evaluate the Efficacy and Safety of OTX-TIC (Travoprost) Intracameral Implant for Patients With Open-angle Glaucoma (OAG) or Ocular Hypertension (OHT)PHASE2 · COMPLETED · started Mar 16, 2022ClinicalTrials.gov NCT05335122 · fetched Nov 12, 2026
- The SITE Study - Dexamethasone Ophthalmic Insert In OR on Day of Surgery Versus In-office Post-Op Day 1PHASE4 · COMPLETED · started Dec 13, 2021ClinicalTrials.gov NCT05143281 · fetched Nov 12, 2026
- In Clinic Optometrist Insertion of Dextenza Prior to Cataract SurgeryPHASE4 · COMPLETED · started Aug 23, 2021ClinicalTrials.gov NCT05023304 · fetched Nov 12, 2026
- Study Evaluating the Treatment of OTX-TKI for Subjects With Neovascular Age-related Macular DegenerationPHASE1 · COMPLETED · started Jul 28, 2021ClinicalTrials.gov NCT04989699 · fetched Nov 12, 2026
- A Human Factors Study to Evaluate a Novel Intracanalicular Insertion Device in Healthy SubjectsEARLY_PHASE1 · TERMINATED · started Jun 1, 2021ClinicalTrials.gov NCT04945824 · fetched Nov 12, 2026
- To Assess the Efficacy and Safety of OTX-DED for the Short-term Treatment of Signs and Symptoms of Dry Eye DiseasePHASE2 · COMPLETED · started Feb 12, 2021ClinicalTrials.gov NCT04747977 · fetched Nov 12, 2026
- Effect on Pain and Inflammation With DEXTENZA Treatment in Patients Undergoing Intravitreal Anti-VEGF InjectionsPHASE4 · TERMINATED · started Dec 9, 2020ClinicalTrials.gov NCT04563299 · fetched Nov 12, 2026
- A Study Assessing the Safety and Efficacy of Dextenza® for the Treatment of Ocular Pain and Inflammation Following Surgery for Pediatric CataractPHASE3 · COMPLETED · started Sep 4, 2020ClinicalTrials.gov NCT04539548 · fetched Nov 12, 2026
- Intracanalicular Dexamethasone Insert for the Treatment of Inflammation and Discomfort in Dry Eye Disease (DEcIDED)PHASE4 · TERMINATED · started Sep 4, 2020ClinicalTrials.gov NCT04527887 · fetched Nov 12, 2026
- Assessing the Efficacy and Safety of DEXTENZA in Pseudo Phakic Patients Undergoing Gas Bubble Repair and Laser Following Retinal DetachmentPHASE4 · TERMINATED · started Jul 14, 2020ClinicalTrials.gov NCT04464629 · fetched Nov 12, 2026
- The RESTORE Study, A Randomized, Controlled, Masked (Reading Center) Prospective StudyPHASE4 · COMPLETED · started Jun 8, 2020ClinicalTrials.gov NCT04396990 · fetched Nov 12, 2026
- Dextenza in the Post-op Management of Vitreoretinal SurgeriesPHASE4 · RECRUITING · started Jun 1, 2020ClinicalTrials.gov NCT04371445 · fetched Nov 12, 2026
- Study to Evaluate the Safety, Tolerability, and Efficacy of OTX-CSI in Subjects With Dry Eye Disease.PHASE1_PHASE2 · COMPLETED · started Apr 23, 2020ClinicalTrials.gov NCT04362670 · fetched Nov 12, 2026
- Intracanalicular Dexamethasone Insert for Post-Corneal Cross-Linking Inflammation and Pain- The LINK StudyPHASE4 · COMPLETED · started Feb 12, 2020ClinicalTrials.gov NCT04168112 · fetched Nov 12, 2026
- Prospective Study on DEXTENZA® Safety And Efficacy Following Concomitant MIGS and Cataract SurgeryPHASE4 · TERMINATED · started Jan 13, 2020ClinicalTrials.gov NCT04200651 · fetched Nov 12, 2026
- Omidria and Dexycu, or Omidria and Dextenza Compared to Topical Prednisolone Acetate 1% Following Cataract SurgeryPHASE4 · COMPLETED · started Dec 10, 2019ClinicalTrials.gov NCT04316936 · fetched Nov 12, 2026
- A Study to Evaluate the Long Term Safety of OTX-TP (Sustained Release Travoprost) Intracanalicular InsertPHASE3 · COMPLETED · started Jul 10, 2018ClinicalTrials.gov NCT04061044 · fetched Nov 12, 2026
- CLN-0045: Safety, and Efficacy of OTX-TIC in Participants With Open Angle Glaucoma or Ocular HypertensionPHASE1 · COMPLETED · started Apr 25, 2018ClinicalTrials.gov NCT04360174 · fetched Nov 12, 2026
SEC filings12
- 8-K · FORM 8-KSEC EDGAR · filed Nov 9, 2026 · fetched Nov 12, 2026
- 10-Q · 10-QSEC EDGAR · filed Nov 9, 2026 · fetched Nov 12, 2026
- 8-K · FORM 8-KSEC EDGAR · filed Nov 9, 2026 · fetched Nov 12, 2026
- 8-K · FORM 8-KSEC EDGAR · filed Oct 16, 2026 · fetched Nov 12, 2026
- 10-Q · 10-QSEC EDGAR · filed Aug 3, 2026 · fetched Nov 12, 2026
- 8-K · FORM 8-KSEC EDGAR · filed Aug 3, 2026 · fetched Nov 12, 2026
- 8-K · FORM 8-KSEC EDGAR · filed Jun 12, 2026 · fetched Nov 12, 2026
- 10-Q · 10-QSEC EDGAR · filed May 5, 2026 · fetched Nov 12, 2026
- 8-K · FORM 8-KSEC EDGAR · filed May 5, 2026 · fetched Nov 12, 2026
- 8-K · FORM 8-KSEC EDGAR · filed Feb 27, 2026 · fetched Nov 12, 2026
- 10-K · 10-KSEC EDGAR · filed Feb 5, 2026 · fetched Nov 12, 2026
- 8-K · FORM 8-KSEC EDGAR · filed Feb 5, 2026 · fetched Nov 12, 2026