Biotech · Private company · Yardley, PA, US

OptiNose, Inc.

SEC CIK 0001494650

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Clinical trials51 recruiting or active

Pipeline programs4From trials and the company's site

Disclosed deals0None found yet

Cash runwayNot availablePrivate: no SEC financials

Pipeline4

Fluticasone PropionatePhase 3 · Nasal PolyposisClinicalTrials.gov · fetched Nov 12, 2026
OPN-375Phase 3 · Bilateral Nasal PolyposisClinicalTrials.gov · fetched Nov 12, 2026
OPN-375Phase 3 · Chronic RhinosinusitisClinicalTrials.gov · fetched Nov 12, 2026
OPN-375Phase 3 · Chronic Rhinosinusitis Without Nasal PolypsClinicalTrials.gov · fetched Nov 12, 2026

Efficacy and Safety of 186 mcg of OPN-375 Nasal Spray Twice a Day (BID) in Adolescents With Chronic Rhinosinusitis Without Nasal PolypsPHASE3 · RECRUITING · started Jul 28, 2025ClinicalTrials.gov NCT06850805 · fetched Nov 12, 2026
Study Evaluating the Efficacy and Safety of Intranasal Administration of OPN-375 in Subjects With Chronic Rhinosinusitis Without the Presence of Nasal PolypsPHASE3 · COMPLETED · started Jun 6, 2019ClinicalTrials.gov NCT03960580 · fetched Nov 12, 2026
OPN-375 Efficacy and Safety in Adolescents With Bilateral Nasal PolypsPHASE3 · COMPLETED · started Dec 31, 2018ClinicalTrials.gov NCT03747458 · fetched Nov 12, 2026
Study Evaluating the Efficacy and Safety of Intranasal Administration of OPN-375 in Subjects With Chronic Rhinosinusitis With or Without the Presence of Nasal PolypsPHASE3 · COMPLETED · started Nov 27, 2018ClinicalTrials.gov NCT03781804 · fetched Nov 12, 2026
Efficacy & Safety of OPN-375 Adults With Bilateral Nasal Polyps Using Nasoendoscopic VideoPHASE3 · COMPLETED · started Jun 7, 2018ClinicalTrials.gov NCT03591068 · fetched Nov 12, 2026