Biotech · Private company

Smith & Nephew, Inc.

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Clinical trials2521 recruiting or active

Pipeline programs26From trials and the company's site

Disclosed deals0None found yet

Cash runwayNot availablePrivate: no SEC financials

Pipeline26

AETOSShoulder OsteoarthritisClinicalTrials.gov · fetched Nov 12, 2026
ALLEVYN◊ COMPLETE CARE SacrumPressure Ulcers (Hospital-acquired Pressure Injuries)ClinicalTrials.gov · fetched Nov 12, 2026
CATALYSTEMTotal Hip Arthroplasty (THA)ClinicalTrials.gov · fetched Nov 12, 2026
Cemented CoCrInflammatory ArthritisClinicalTrials.gov · fetched Nov 12, 2026
Cemented OxiniumInflammatory ArthritisClinicalTrials.gov · fetched Nov 12, 2026
CementlessInflammatory ArthritisClinicalTrials.gov · fetched Nov 12, 2026
Completion and RepairRotator Cuff InjuriesClinicalTrials.gov · fetched Nov 12, 2026
CORI™ KNEE TENSIONERArthroplastyClinicalTrials.gov · fetched Nov 12, 2026
Iontophoresis and tube placementOtitis Media With EffusionClinicalTrials.gov · fetched Nov 12, 2026
Isolated Bioinductive RepairRotator Cuff InjuriesClinicalTrials.gov · fetched Nov 12, 2026
JOURNEY II XR Total Knee SystemRheumatoid Vasculitis With Rheumatoid Arthritis of KneeClinicalTrials.gov · fetched Nov 12, 2026
Journey UNI Unicompartmental Knee SystemNon-inflammatory Degenerative Joint DiseaseClinicalTrials.gov · fetched Nov 12, 2026
JOURNEY™ II CR Total Knee System (J II CR TKS)Osteoarthritis, KneeClinicalTrials.gov · fetched Nov 12, 2026
LEGION Hinge Knee SystemKnee Arthroplasty, TotalClinicalTrials.gov · fetched Nov 12, 2026
LEGION Porous HA Tibial Baseplate and/or the LEGION Porous HA CR Femoral ComponentTotal Knee ArthroplastyClinicalTrials.gov · fetched Nov 12, 2026
Legion™ CR Oxinium and CoCr Femoral Implants combined with Legion™/Genesis™ II XLPE High Flex Tibial InsertsTotal Knee ArthroplastyClinicalTrials.gov · fetched Nov 12, 2026
Marketed Product - MP01Knee InjuriesClinicalTrials.gov · fetched Nov 12, 2026
MICRORAPTOR™ Knotless PEEK Suture AnchorLabral Tear, GlenoidClinicalTrials.gov · fetched Nov 12, 2026
MICRORAPTOR™ Knotless REGENESORB™ Suture AnchorLabral Tear, GlenoidClinicalTrials.gov · fetched Nov 12, 2026
MICRORAPTOR™ REGENESORB™ Suture AnchorLabral Tear, GlenoidClinicalTrials.gov · fetched Nov 12, 2026
Other Surgical TreatmentsKnee InjuriesClinicalTrials.gov · fetched Nov 12, 2026
Primary Total Hip ArthroplastyAdvanced Degeneration of the Hip JointClinicalTrials.gov · fetched Nov 12, 2026
REDAPTHip ReplacementClinicalTrials.gov · fetched Nov 12, 2026
RENASYS◊ DYNAFLOW Instillation TherapyWounds and InjuriesClinicalTrials.gov · fetched Nov 12, 2026
Revision Total Hip ArthroplastyAdvanced Degeneration of the Hip JointClinicalTrials.gov · fetched Nov 12, 2026
Total Knee ArthroplastyOsteoarthritisClinicalTrials.gov · fetched Nov 12, 2026

Clinical trials25

Sacrum Pressure Injury Prevention Study Using ALLEVYN◊ Complete Care in Adults at Risk of Developing Hospital-acquired Pressure Injuries in Critical Care UnitsNA · NOT_YET_RECRUITING · started Oct 30, 2026ClinicalTrials.gov NCT07849387 · fetched Nov 12, 2026
Utilizing RENASYS◊ DYNAFLOW Instillation Therapy System for Wound Management in Adults With Acute and Chronic WoundsNA · NOT_YET_RECRUITING · started Oct 30, 2026ClinicalTrials.gov NCT07899814 · fetched Nov 12, 2026
Knee Cartilage Repair RegistryRECRUITING · started Sep 23, 2026ClinicalTrials.gov NCT07786207 · fetched Nov 12, 2026
A Multi-Center Study Assessing the Safety and Efficacy of the LEGION Medial Stabilized (MS) Insert in Patients Undergoing a Total Knee Arthroplasty (TKA)RECRUITING · started Sep 25, 2025ClinicalTrials.gov NCT07199738 · fetched Nov 12, 2026
A Post Approval Multicenter 10 Year Follow-up Observational Trial of Marketed Product - MP01 vs. Surgical Standard of Care (SSOC) Used for the Treatment of Joint Surface Lesions of the KneeENROLLING_BY_INVITATION · started May 5, 2025ClinicalTrials.gov NCT06916728 · fetched Nov 12, 2026
A Multi-Centre Study in Patients Undergoing Total Hip Arthroplasty With the Smith+Nephew CATALYSTEM™ Primary Hip SystemACTIVE_NOT_RECRUITING · started Sep 26, 2024ClinicalTrials.gov NCT06564636 · fetched Nov 12, 2026
AETOS Shoulder SystemRECRUITING · started Mar 5, 2024ClinicalTrials.gov NCT06319911 · fetched Nov 12, 2026
Evaluation of Outcomes Following In-office Tympanostomy Using the Tula® System: a Prospective, Multi-center RegistryRECRUITING · started Jun 15, 2023ClinicalTrials.gov NCT05915078 · fetched Nov 12, 2026
Use of the REGENETEN™ Bioinductive Implant System in High Grade Partial-thickness TearsNA · RECRUITING · started Aug 30, 2022ClinicalTrials.gov NCT05444465 · fetched Nov 12, 2026
Prospective Randomized Study of Cementless vs Cemented UKANA · ACTIVE_NOT_RECRUITING · started Aug 29, 2022ClinicalTrials.gov NCT05377450 · fetched Nov 12, 2026
To Evaluate the Performance of the CORI™ KNEE TENSIONER as an Accessory to the CORI™ Surgical System.NA · COMPLETED · started Mar 30, 2022ClinicalTrials.gov NCT04849884 · fetched Nov 12, 2026
A Global Clinical Study Investigating the Safety and Effectiveness of Smith and Nephew's Porous Knee System in Patients Who Need a Total Knee Replacement Due to Degenerative Arthritis, Post-traumatic Arthritis or Inflammatory ArthritisACTIVE_NOT_RECRUITING · started Dec 21, 2021ClinicalTrials.gov NCT05197036 · fetched Nov 12, 2026
Werewolf Flow 50 During ACL ReconstructionNA · COMPLETED · started Jul 12, 2021ClinicalTrials.gov NCT04998656 · fetched Nov 12, 2026
Safety and Effectiveness Study of OR3O™ Dual Mobility System in THAACTIVE_NOT_RECRUITING · started Jul 27, 2020ClinicalTrials.gov NCT04325022 · fetched Nov 12, 2026
Evaluation of Regeneten Augmentation for Subscapularis Healing After Total Shoulder Arthroplasty (RESTOR)NA · ACTIVE_NOT_RECRUITING · started Jul 14, 2020ClinicalTrials.gov NCT04861714 · fetched Nov 12, 2026
Safety and Performance of MICRORAPTOR™ Suture Anchors in Shoulder and HipCOMPLETED · started Aug 1, 2019ClinicalTrials.gov NCT03985839 · fetched Nov 12, 2026
Safety and Performance Study of the Legion Porous System in Total Knee ArthroplastyACTIVE_NOT_RECRUITING · started May 22, 2019ClinicalTrials.gov NCT03720782 · fetched Nov 12, 2026
Navio Robotic Versus Conventional Total Knee ArthroplastyNA · ACTIVE_NOT_RECRUITING · started Apr 17, 2019ClinicalTrials.gov NCT03519269 · fetched Nov 12, 2026
Efficacy Bioinductive Implant for Tennis Elbow (Lateral Epicondylitis)PHASE4 · RECRUITING · started Apr 17, 2019ClinicalTrials.gov NCT03718637 · fetched Nov 12, 2026
Safety and Performance Using Legion™ CR Oxinium and CoCr Femoral Implants Combined With Legion™/Genesis™ II XLPE High Flex Tibial InsertsACTIVE_NOT_RECRUITING · started Aug 26, 2018ClinicalTrials.gov NCT03687593 · fetched Nov 12, 2026
A Multicenter, Post-Market Clinical Follow-up Study of Subjects With the REDAPT™ System Monolithic Sleeveless/Sleeved Stem and/or Fully Porous Acetabular Shell With XLPE Liner and/or Modular Shell Components Previously ImplantedENROLLING_BY_INVITATION · started May 7, 2018ClinicalTrials.gov NCT03610789 · fetched Nov 12, 2026
Journey™ UNI Post Market Clinical Follow-UpCOMPLETED · started Apr 11, 2018ClinicalTrials.gov NCT03442231 · fetched Nov 12, 2026
JOURNEY II XR Safety and Effectiveness PMCFACTIVE_NOT_RECRUITING · started Jul 28, 2017ClinicalTrials.gov NCT03136887 · fetched Nov 12, 2026
JOURNEY™ II CR Total Knee SystemACTIVE_NOT_RECRUITING · started Sep 1, 2015ClinicalTrials.gov NCT02440672 · fetched Nov 12, 2026
LEGION Hinge Safety and Efficacy StudyACTIVE_NOT_RECRUITING · started Jun 30, 2015ClinicalTrials.gov NCT02445443 · fetched Nov 12, 2026