Biotech · Public company · Waltham, MA, US

Spyre Therapeutics, Inc.

Ticker SYRE · SEC CIK 0001636282

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Clinical trials85 recruiting or active

Pipeline programs10From trials and the company's site

Disclosed deals0None found yet

Cash runwayNot availableNo recent cash burn filed

Pipeline10

A Study of SPY072 in Adults With Moderate to Severe Hidradenitis Suppurativa (The SKYLIGHT Trial)PHASE2 · RECRUITING · started Sep 1, 2026ClinicalTrials.gov NCT07766005 · fetched Nov 12, 2026
Long-term Safety and Efficacy of Multiple Long-acting Antibodies Alone and in Combinations for IBDPHASE2 · ENROLLING_BY_INVITATION · started Jun 8, 2026ClinicalTrials.gov NCT07652294 · fetched Nov 12, 2026
A Study of SPY072 in Rheumatic DiseasePHASE2 · ACTIVE_NOT_RECRUITING · started Aug 21, 2025ClinicalTrials.gov NCT07148414 · fetched Nov 12, 2026
A Study of Long-acting Antibodies Alone and in Combinations for Moderate to Severe Ulcerative ColitisPHASE2 · RECRUITING · started May 27, 2025ClinicalTrials.gov NCT07012395 · fetched Nov 12, 2026
A Study of SPY003-207 in Healthy VolunteersPHASE1 · ACTIVE_NOT_RECRUITING · started Mar 10, 2025ClinicalTrials.gov NCT06873724 · fetched Nov 12, 2026
A Study of SPY002-091 in Healthy VolunteersPHASE1 · COMPLETED · started Nov 26, 2024ClinicalTrials.gov NCT06672718 · fetched Nov 12, 2026
A Study of SPY002-072 in Healthy VolunteersPHASE1 · COMPLETED · started Nov 18, 2024ClinicalTrials.gov NCT06622070 · fetched Nov 12, 2026
A Study of SPY001-001 in Healthy VolunteersPHASE1 · COMPLETED · started Jun 6, 2024ClinicalTrials.gov NCT06448247 · fetched Nov 12, 2026